Phenethyl bromide → 1-Phenethyl-3-anilinopyrrolidine

HRID 992274Notes

Reaction equation

HRID 992274 reaction equation
[NH:1]([CH:8]1[CH2:12][CH2:11][NH:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[NH:1]([CH:8]1[CH2:12][CH2:11][N:10]([CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7666Phenethyl bromideHCID 11412557N-phenylpyrrolidin-3-amine

Product 1

HCID 184118371-Phenethyl-3-anilinopyrrolidine

Procedure

3-Anilinopyrrolidine and 2-bromoethylbenzene are reacted under the same conditions as in Starting Material Synthetic Example 4 to give 3-anilino-1-(2-phenylethyl)pyrrolidine.

Sources & evidence

ORD record
ord-bf679b7cfd3046fbb82a264ea66b9981
Source dataset
uspto-grants-2002_10
Patent number
US06468998B1

Reaction notes

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