3-(Methylamino)pyrrolidine → HCID 18411795, compound

HRID 992276Notes

Reaction equation

HRID 992276 reaction equation
[CH3:1][NH:2][CH:3]1[CH2:7][CH2:6][NH:5][CH2:4]1.C1(C)C=CC(S(O[CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=2)(=O)=O)=CC=1>>[CH3:1][NH:2][CH:3]1[CH2:7][CH2:6][N:5]([CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([F:26])=[CH:22][CH:21]=2)[CH2:4]1

Participants

3

Reactant 2

HCID 117882683-(Methylamino)pyrrolidineHCID 17390106Benzeneethanol, 4-fluoro-, 1-(4-methylbenzenesulfonate)

Product 1

HCID 18411795HCID 18411795, compound

Procedure

3-Methylaminopyrrolidine and 2-(4-fluorophenyl)ethyl p-toluenesulfonate are reacted under the same conditions as in Starting Material Synthetic Example 4 to give 3-methylamino-1-(2-(4-fluorophenyl)ethyl)pyrrolidine.

Sources & evidence

ORD record
ord-91e92b9bbcd54c5a902e437f12a36a00
Source dataset
uspto-grants-2002_10
Patent number
US06468998B1

Reaction notes

Loading…