HCID 13058050, compound → HCID 9951729, compound

HRID 992293Notes

Reaction equation

HRID 992293 reaction equation
[NH:1]1[CH2:5][CH2:4][C@H:3]([NH:6][C:7]([C:9]23[CH2:18][CH:13]4[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]4)[CH2:10]2)[CH2:16]3)=[O:8])[CH2:2]1.C1(C)C=CC(S(O[CH2:29][CH:30]2[C:38]3[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=3)[CH2:32][CH2:31]2)(=O)=O)=CC=1>>[CH:30]1([CH2:29][N:1]2[CH2:5][CH2:4][C@H:3]([NH:6][C:7]([C:9]34[CH2:18][CH:13]5[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]5)[CH2:10]3)[CH2:16]4)=[O:8])[CH2:2]2)[C:38]2[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 13058050HCID 13058050, compoundHCID 49760538(S)-N-(pyrrolidin-3-yl)-1-adamantanecarboxamide

Product 1

HCID 9951729HCID 9951729, compound

Procedure

(S)-N-(Pyrrolidin-3-yl)-1-adamantanecarboxamide and (2,3-dihydroinden-1-yl)methyl p-toluenesulfonate were reacted under the same conditions as in Example 6 to give (S)-N-(1-((2,3-dihydroinden-1-yl)methyl)pyrrolidin-3-yl)-1-adamantanecarboxamide.

Sources & evidence

ORD record
ord-c4bbc8645a7f4d0c9d764cf6d595d88b
Source dataset
uspto-grants-2002_10
Patent number
US06468998B1

Reaction notes

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