HCID 11174534, compound → HCID 59915898, compound

HRID 992294Notes

Reaction equation

HRID 992294 reaction equation
[NH:1]1[CH2:5][CH2:4][C@H:3]([NH:6][C:7]([C:9]23[CH2:18][CH:13]4[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]4)[CH2:10]2)[CH2:16]3)=[O:8])[CH2:2]1.C1(C)C=CC(S(O[CH2:29][CH:30]2[CH2:39][CH2:38][C:37]3[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=3)[CH2:31]2)(=O)=O)=CC=1>>[CH2:31]1[C:32]2[C:37](=[CH:36][CH:35]=[CH:34][CH:33]=2)[CH2:38][CH2:39][CH:30]1[CH2:29][N:1]1[CH2:5][CH2:4][C@H:3]([NH:6][C:7]([C:9]23[CH2:18][CH:13]4[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]4)[CH2:10]2)[CH2:16]3)=[O:8])[CH2:2]1

Participants

3

Reactant 2

HCID 11174534HCID 11174534, compoundHCID 49760538(S)-N-(pyrrolidin-3-yl)-1-adamantanecarboxamide

Product 1

HCID 59915898HCID 59915898, compound

Procedure

(S)-N-(Pyrrolidin-3-yl)-1-adamantanecarboxamide and (1,2,3,4-tetrahydronaphthalen-2-yl)methyl p-toluenesulfonate were reacted under the same conditions as in Example 6 to give (S)-N-(1-((1,2,3,4-tetrahydronaphthalen-2-yl)methyl)pyrrolidin-3-yl)-1-adamantanecarboxamide.

Sources & evidence

ORD record
ord-7a0e7dc91ae748a789ee8d82072604f2
Source dataset
uspto-grants-2002_10
Patent number
US06468998B1

Reaction notes

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