Phenethyl bromide → HCID 59915871, compound

HRID 992313Notes

Reaction equation

[CH3:1][N:2]([C@H:15]1[CH2:19][CH2:18][NH:17][CH2:16]1)[C:3]([C:5]12[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][CH:7]([CH2:8]3)[CH2:6]1)[CH2:12]2)=[O:4].Br[CH2:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH3:1][N:2]([C@H:15]1[CH2:19][CH2:18][N:17]([CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:16]1)[C:3]([C:5]12[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][CH:7]([CH2:8]3)[CH2:6]1)[CH2:12]2)=[O:4]

Participants

Reactant 2

HCID 7666Phenethyl bromide

HCID 70173564HCID 70173564, compound

Product 1

HCID 59915871HCID 59915871, compound

Procedure

(S)-N-Methyl-N-(pyrrolidin-3-yl)-1-adamantanecarboxamide and (2-bromoethyl)benzene were reacted under the same conditions as in Example 1 to give (S)-N-methyl-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-1-adamantanecarboxamide.

Sources & evidence

ORD record: ord-82baa91ea95e47589b9e0348602f20d8
Source dataset: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06468998B1

Reaction notes

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