HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylquinuclidine-3-carbonyl chloride → (S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-4-methylquinuclidine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylquinuclidine-3-carbonyl chloride | HCID 18411874 | — |
| Reactant | (S)-3-amino-1-(2-(4-fluorophenyl)ethyl)pyrrolidine | HCID 59915932 | — |
| Product | (S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-4-methylquinuclidine-3-carboxamide | HCID 70173453 | — |
Reaction Steps
4-Methylquinuclidine-3-carbonyl chloride and (S)-3-amino-1-(2-(4-fluorophenyl)ethyl)pyrrolidine were reacted under the same conditions as in Example 53 to give (S)-N-(1-(2-(4-fluorophenyl)ethyl)pyrrolidin-3-yl)-4-methylquinuclidine-3-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06468998B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-d20ed92725774f2f8d3eacc6f24bd4ec |
| Source note | uspto-grants-2002_10 |