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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992337Generated: November 1, 2026

(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine → (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-2-bicyclo[2.2.2]octanecarboxamide

https://huagongshe.com/reaction/992337

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-1-(2-Phenylethyl)-3-pyrrolidinamineHCID 10774056—
ReactantBicyclo[2.2.2]octane-2-carbonyl chlorideHCID 18411844—
Product(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-2-bicyclo[2.2.2]octanecarboxamideHCID 70176408—

Reaction Steps

2-Bicyclo[2.2.2]octanecarbonyl chloride and (S)-3-amino-1-(2-phenylethyl)pyrrolidine were reacted under the same conditions as in Example 53 to give (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)-2-bicyclo[2.2.2]octanecarboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06468998B1
Source datasetuspto-grants-2002_10
ORD IDord-47e839814f3147a5a5a8e0dd08c442a1
Source noteuspto-grants-2002_10