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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992344Generated: October 27, 2026

(3S)-1-(2-Phenylethyl)-3-pyrrolidinamine → (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)quinuclidine-2-carboxamide

https://huagongshe.com/reaction/992344

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-1-(2-Phenylethyl)-3-pyrrolidinamineHCID 10774056—
ReactantQuinuclidine-2-carbonyl chlorideHCID 12216970—
Product(S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)quinuclidine-2-carboxamideHCID 70173580—

Reaction Steps

Quinuclidine-2-carbonyl chloride and (S)-3-amino-1-(2-phenylethyl)pyrrolidine were reacted under the same conditions as in Example 53 to give (S)-N-(1-(2-phenylethyl)pyrrolidin-3-yl)quinuclidine-2-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06468998B1
Source datasetuspto-grants-2002_10
ORD IDord-9c72a07aafd54af3a42f399b082f4e3e
Source noteuspto-grants-2002_10