2-(Bromomethyl)-2-phenyl-1,3-dioxolane → 2-[4-(4-Phenoxyphenyl)piperidin-1-yl]methyl-2-phenyl-1,3-dioxolane

HRID 992378노트

반응식

HRID 992378 반응식
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:21][C:22]1([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[O:26][CH2:25][CH2:24][O:23]1>>[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][N:17]([CH2:21][C:22]3([C:27]4[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=4)[O:23][CH2:24][CH2:25][O:26]3)[CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 2915742-(Bromomethyl)-2-phenyl-1,3-dioxolaneHCID 110759844-(4-Phenoxyphenyl)piperidine

생성물 1

HCID 187944852-[4-(4-Phenoxyphenyl)piperidin-1-yl]methyl-2-phenyl-1,3-dioxolane

실험 절차

The same procedure was followed as in Example 11 using the compound (9) synthesized in Example 2 and 2-bromomethyl-2-phenyl-1,3-dioxolane to produce the above.

후처리

  1. customto produce the above

출처 및 근거

ORD 기록
ord-08b455e234ff4675a18fdc1fb4917a34
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06469010B1

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