HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69749406, compound → HCID 86584273, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69749406 | HCID 69749406 | — |
| Reactant | HCID 178418634 | HCID 178418634 | — |
| Product | HCID 86584273 | HCID 86584273 | 95% |
Reaction Steps
4-(1-Carboxy-vinyl)-piperidine-1-carboxylic acid benzyl ester (15.6 g) was dissolved in thioacetic acid (15 ml) and heated to reflux for 3 h. The thioacetic acid was evaporated under reduced pressure and azeotroped with 1:1 hexane-dichloromethane (4×30 ml) to give the title compound (20.32 g, 95%) as an orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06469020B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-5782219c95f843a3811bc98fd489c1db |
| Source note | uspto-grants-2002_10 |