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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992621Generated: October 30, 2026

Hydrochloric Acid → 1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide hydrochloride

https://huagongshe.com/reaction/992621

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAmmonium CarbonateHCID 517111—
ReactantHCID 18412582HCID 18412582—
SolventEthanolHCID 702—
Product1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide hydrochlorideHCID 18412709—

Reaction Steps

Prepared analogously to Example 25d from 1-methyl-2-[2-(4-cyanophenyl)ethyl]-benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)-amide and ethanolic hydrochloric acid, ethanol and ammonium carbonate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06469039B1
Source datasetuspto-grants-2002_10
ORD IDord-76e9e06da4784bdebec4395e075c1fe8
Source noteuspto-grants-2002_10