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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992780Generated: November 1, 2026

p-Fluoronitrobenzene → 1-Nitro-4-phenoxybenzene

https://huagongshe.com/reaction/992780

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-FluoronitrobenzeneHCID 9590—
ReactantPhenolate SodiumHCID 4445035—
Product1-Nitro-4-phenoxybenzeneHCID 1211098%

Reaction Steps

The reaction was carried out completely in the same manner as in Example 21, except that p-fluoronitrobenzene was used instead of p-chloronitrobenzene and sodium phenolate was used instead of potassium fluoride in Example 21. Further, the reaction temperature was changed to 80° C. and the reaction time was changed to 3 hours without pursuing the reaction on halfway. Objective 4-phenoxynitrobenzene was produced in the yield of 98%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06469224B1
Source datasetuspto-grants-2002_10
ORD IDord-b163d26c1bb8485f8e8c80b0e727b98d
Source noteuspto-grants-2002_10