4-(1H-Pyrazol-1-yl)benzaldehyde → 3-[4-(5-Pyrimidinyl)phenyl]-2-propenal

HRID 992944Notes

Reaction equation

HRID 992944 reaction equation
[N:1]1[CH:6]=[C:5]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)[CH:4]=[N:3][CH:2]=1.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[C:5]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=[CH:23][CH:24]=[O:25])=[CH:9][CH:8]=2)[CH:4]=[N:3][CH:2]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 38612125-(4-Formylphenyl)pyrimidine

Product 1

HCID 739903923-[4-(5-Pyrimidinyl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(5-pyrimidinyl)-benzaldehyde (prepared as described in WO 9828264) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 211 (M+H)+.

Sources & evidence

ORD record
ord-9e860c1b4f78486dab0b790640e14722
Source dataset
uspto-grants-2002_10
Patent number
US06472372B1

Reaction notes

Loading…