4-(1H-Pyrazol-1-yl)benzaldehyde → HCID 73990391, compound

HRID 992954Notes

Reaction equation

HRID 992954 reaction equation
[CH3:1][N:2]1[C:6]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)=[CH:5][CH:4]=[N:3]1.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[CH3:1][N:2]1[C:6]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=[CH:23][CH:24]=[O:25])=[CH:9][CH:8]=2)=[CH:5][CH:4]=[N:3]1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 106551454-(1-methyl-1H-pyrazol-5-yl)benzaldehyde

Product 1

HCID 73990391HCID 73990391, compound

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(1-methyl-1H-pyrazol-5-yl)benzaldehyde (prepared as described in J. Med. Chem. 1998, 41, 2390) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 213 (M+H)+.

Sources & evidence

ORD record
ord-287e428413864216bc7755f1c09b3353
Source dataset
uspto-grants-2002_10
Patent number
US06472372B1

Reaction notes

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