8-Quinolinecarboxaldehyde → 3-(8-Quinolinyl)-2-propenal

HRID 992956Notes

Reaction equation

HRID 992956 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[CH:11]=O)[CH:4]=[CH:3][CH:2]=1.N1(C2C=C[C:21]([CH:22]=[O:23])=CC=2)C=CC=N1>>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[CH:11]=[CH:21][CH:22]=[O:23])[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 1701038-QuinolinecarboxaldehydeHCID 27764774-(1H-Pyrazol-1-yl)benzaldehyde

Product 1

HCID 731589903-(8-Quinolinyl)-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 8-quinolinecarboxaldehyde (prepared as described in J. Am. Chem. Soc. 1997, 119, 8891) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 184 (M+H)+.

Sources & evidence

ORD record
ord-0e17381574bb4490bfc5a8d888d8848c
Source dataset
uspto-grants-2002_10
Patent number
US06472372B1

Reaction notes

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