4-(1H-Pyrazol-1-yl)benzaldehyde → 3-[3-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-2-propenal

HRID 992961Notes

Reaction equation

HRID 992961 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:10]1[CH:14]=[N:13][CH:12]=[N:11]1)[CH:5]=O.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:23][CH:24]=[O:25])[CH:7]=[CH:8][C:9]=1[N:10]1[CH:14]=[N:13][CH:12]=[N:11]1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 162279523-fluoro-4-(1H-1,2,4-triazol-1-yl)benzaldehyde

Product 1

HCID 739903813-[3-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 3-fluoro-4-(l H-1,2,4-triazol-1-yl)benzaldehyde (prepared as described in Reference Example 7) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 218 (M+H)+.

Sources & evidence

ORD record
ord-3a866f13fbbc4946ab87a0c7f0be82ac
Source dataset
uspto-grants-2002_10
Patent number
US06472372B1

Reaction notes

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