4-(Pyrimidin-2-yloxy)benzaldehyde → 3-[4-(2-Pyrimidinyloxy)phenyl]-2-propenal

HRID 992968Notes

Reaction equation

HRID 992968 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[O:7][C:8]1[CH:15]=[CH:14][C:11]([CH:12]=O)=[CH:10][CH:9]=1.N1(C2C=C[C:24]([CH:25]=[O:26])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[O:7][C:8]1[CH:15]=[CH:14][C:11]([CH:12]=[CH:24][CH:25]=[O:26])=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 27635624-(Pyrimidin-2-yloxy)benzaldehydeHCID 27764774-(1H-Pyrazol-1-yl)benzaldehyde

Product 1

HCID 739903783-[4-(2-Pyrimidinyloxy)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(2-pyrimidinyloxy)benzaldehyde (prepared as described in Reference Example 9) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 227 (M+H)+.

Sources & evidence

ORD record
ord-480cdc5e2bda4f4c841c3845029bea18
Source dataset
uspto-grants-2002_10
Patent number
US06472372B1

Reaction notes

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