Toluene → 2-{5-[Bis-(2-methoxy-ethyl)-amino]-pyridin-2-ylamino}-6-bromo-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Reaction equation
[Br:1][c:2]1[c:3]([CH3:21])[c:4]2[c:5]([n:6][c:7]([S:10]([CH3:11])=[O:12])[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15].[CH3:22][O:23][CH2:24][CH2:25][N:26]([c:27]1[cH:28][cH:29][c:30]([NH2:33])[n:31][cH:32]1)[CH2:34][CH2:35][O:36][CH3:37].[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1>>[Br:1][c:2]1[c:3]([CH3:21])[c:4]2[c:5]([n:6][c:7]([NH:33][c:30]3[cH:29][cH:28][c:27]([N:26]([CH2:25][CH2:24][O:23][CH3:22])[CH2:34][CH2:35][O:36][CH3:37])[cH:32][n:31]3)[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-67d6d4d5e9744c17bcc22aab76e4efa3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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