HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 3-[4-(2,6-Di-t-butylpyrimidin-4-yl)piperazin-1-yl]propyl-triphenylphosphonium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 2-tert-Butyl-4-[4-(3-chloro-propyl)-piperazin-1-yl]-6-tert-butyl-pyrimidine | HCID 22349871 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-[4-(2,6-Di-t-butylpyrimidin-4-yl)piperazin-1-yl]propyl-triphenylphosphonium chloride | HCID 18408603 | — |
Reaction Steps
3.52 g (10 mmol) of 1-chloro-3-[4-(2,6-di-t-butylpyrimidin-4-yl)piperazin-1-yl]propane (prepared by a method similar to Example 1, A.3) were dissolved, together with 1.8 g of sodium iodide (12 mmol) and 3.41 g (13 mmol) of triphenylphosphine in 75 ml of acetone and the solution was refluxed for 24 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472392B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-dcf51093b9c94bc6ab441dac47be714b |
| Source note | uspto-grants-2002_10 |