Water → HCID 18408501, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl 2-(3,4,5-trimethoxyphenyl)thiazole-4-carboxylate (6.9 g) was dissolved in THF (100 mL), and to the solution lithium aluminum hydride (810 mg) was added under an argon atmosphere, and the mixture was stirred at 0° C. for 1 hour. After a small amount of water and then sodium sulfate were added to the reaction mixture, the reaction mixture was filtered through celite, and the filtrate was concentrated under reduced pressure. The resultant crude crystals were recrystallized from ethyl acetate-hexane to obtain the title compound.

Provenance & Evidence