Hexahydro-1,4-diazepine → HCID 10146282, compound

HRID 992992Notes

Reaction equation

HRID 992992 reaction equation
CS(O[CH2:6][CH2:7][C:8]1[N:9]=[C:10]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[C:16]([O:21][CH3:22])=[C:15]([O:23][CH3:24])[CH:14]=2)[S:11][CH:12]=1)(=O)=O.[NH:25]1[CH2:31][CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[CH3:24][O:23][C:15]1[CH:14]=[C:13]([C:10]2[S:11][CH:12]=[C:8]([CH2:7][CH2:6][N:25]3[CH2:31][CH2:30][CH2:29][N:28]([CH2:6][CH2:7][C:8]4[N:9]=[C:10]([C:13]5[CH:14]=[C:15]([O:23][CH3:24])[C:16]([O:21][CH3:22])=[C:17]([O:19][CH3:20])[CH:18]=5)[S:11][CH:12]=4)[CH2:27][CH2:26]3)[N:9]=2)[CH:18]=[C:17]([O:19][CH3:20])[C:16]=1[O:21][CH3:22]

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 18408483HCID 18408483, compound

Product 1

HCID 10146282HCID 10146282, compound

Procedure

4-(2-Methanesulfonyloxyethyl)-2-(3,4,5-trimethoxy-phenyl)thiazole (250mg) and homopiperazine (30mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-a65f33073bae4e48b93175a15a4cc058
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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