HCID 67526446, compound → HCID 18408532, compound

Participants

Reaction Steps

Ethyl 3-[2-(3,4,5-trimethoxyphenyl)thiazol-4-yl]propenoate (1.65 g) was suspended in methanol (20 mL), 10% palladium on carbon (800 mg) was added to the suspension under an argon atmosphere, and the mixture was stirred at room temperature under a hydrogen amosphere. The reaction mixture was filtered, the filtrate was concentrated, and the residue was purified by column chromatography on silica gel (hexane:ethyl acetate=3:1 to 1:1) to obtain the title compound.

Provenance & Evidence