Hexahydro-1,4-diazepine → HCID 10121857, compound

HRID 993010Notes

Reaction equation

HRID 993010 reaction equation
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=2)[N:5]([CH3:20])[N:4]=1.[NH:21]1[CH2:27][CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH3:20][N:5]1[C:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=2)=[CH:7][C:3]([CH2:2][N:21]2[CH2:27][CH2:26][CH2:25][N:24]([CH2:2][C:3]3[CH:7]=[C:6]([C:8]4[CH:9]=[C:10]([O:18][CH3:19])[C:11]([O:16][CH3:17])=[C:12]([O:14][CH3:15])[CH:13]=4)[N:5]([CH3:20])[N:4]=3)[CH2:23][CH2:22]2)=[N:4]1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 18408523HCID 18408523, compound

Product 1

HCID 10121857HCID 10121857, compound

Procedure

3-Chloromethyl-1-methyl-5-(3,4,5-trimethoxy-phenyl)pyrazole (119 mg) and homopiperazine (20 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-9a3b9f905c974e0982c46e66dacf2154
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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