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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 993011Generated: October 31, 2026

Piperazine → N,N'-bis[[1-Methyl-3-(3,4,5-trimethoxy-phenyl)pyrazol-5-yl]methyl]piperazine

https://huagongshe.com/reaction/993011

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant5-Chloromethyl-1-methyl-3-(3,4,5-trimethoxy-phenyl)pyrazoleHCID 18408486—
ProductN,N'-bis[[1-Methyl-3-(3,4,5-trimethoxy-phenyl)pyrazol-5-yl]methyl]piperazineHCID 10121602—

Reaction Steps

5-Chloromethyl-1-methyl-3-(3,4,5-trimethoxy-phenyl)pyrazole (119 mg) and piperazine (17 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06472386B1
Source datasetuspto-grants-2002_10
ORD IDord-a82ab5ba8c2b48d4932c5b5c2722a312
Source noteuspto-grants-2002_10