Hydrazine, (phenylmethyl)-, hydrochloride (1:1) → HCID 18408493, compound

HRID 993013Notes

Reaction equation

HRID 993013 reaction equation
O[C:2]([C:11]1[CH:16]=[C:15]([O:17][CH3:18])[C:14]([O:19][CH3:20])=[C:13]([O:21][CH3:22])[CH:12]=1)=[CH:3][C:4](=O)[C:5]([O:7][CH2:8][CH3:9])=[O:6].Cl.[CH2:24]([NH:31][NH2:32])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:24]([N:31]1[C:2]([C:11]2[CH:16]=[C:15]([O:17][CH3:18])[C:14]([O:19][CH3:20])=[C:13]([O:21][CH3:22])[CH:12]=2)=[CH:3][C:4]([C:5]([O:7][CH2:8][CH3:9])=[O:6])=[N:32]1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 14084Hydrazine, (phenylmethyl)-, hydrochloride (1:1)HCID 67524928HCID 67524928, compound

Product 1

HCID 18408493HCID 18408493, compound

Procedure

Ethyl 4-hydroxy-2-oxo-4-(3,4,5-trimethoxyphenyl)-3-butenoate (3.12 g) and benzylhydrazine hydrochloride (1.59 g) were treated in the same manner as in Preparation Example 26 to obtain the title compound.

Sources & evidence

ORD record
ord-64d312a0faa744ab95856914573957c9
Source dataset
uspto-grants-2002_10
Patent number
US06472386B1

Reaction notes

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