2-Methyldodecanoic acid → 2,2-Dimethyldodecanoyl chloride

HRID 993046Notes

Reaction equation

HRID 993046 reaction equation
[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:3]([Cl:5])=[O:4].[CH3:16]C(CCCCCCCCCC)C(O)=O>>[CH3:1][C:2]([CH3:16])([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:3]([Cl:5])=[O:4]

Participants

3

Reactant 2

HCID 1028932-Methyldodecanoic acidHCID 22595332HCID 22595332, compound

Product 1

HCID 156564322,2-Dimethyldodecanoyl chloride

Procedure

In a similar manner to that described in Example 25 except for the use of 2-methyldodecanoyl chloride [synthesized by chlorinating 2-methyldodecanoic acid which was synthesized by the process described in Organic Synthesis, 4,616, by the method as described in B. D. Roth. et al., Journal of Medicinal Chemistry, 35, 1609-1617 (1992)] instead of 2,2-dimethyldodecanoyl chloride, 82.5 mg of the desired compound was obtained as a white powder.

Workup

  1. customsynthesized
  2. customwas synthesized by the process
  3. customdescribed in Organic Synthesis, 4,616, by the method

Sources & evidence

ORD record
ord-6a990363e33945e4a3a65b4b4acc235c
Source dataset
uspto-grants-2002_10
Patent number
US06472384B1

Reaction notes

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