HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Hydroxyethyl)piperazine → HCID 18408714, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Hydroxyethyl)piperazine | HCID 7677 | — |
| Reactant | HCID 18408764 | HCID 18408764 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 18408714 | HCID 18408714 | 14.1% |
Reaction Steps
A solution of 5-[3-(tertbutyldimethylsilyloxy)phenyl]-5-bromobarbituric Acid (444 mg) and N-(2-hydroxyethyl)piperazine (420 mg) in 10 ml of methanol is stirred at room temperature for 5 hours, then the solvent is evaporated off and the residue is purified by silica gel chromatography (13 g, eluent:ethyl acetate/methanol 3:1), to give 70 mg of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472396B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-12a37b26cbfb4cf5bb73a3da38986d70 |
| Source note | uspto-grants-2002_10 |