Homoallyl bromide → N-(3-Buten-1-yl)phthalimide

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of 4-bromo-1-butene (20 g, 148 mmol) in DMF (150 mL) was added potassium phthalimide (25 g, 133 mmol) and the mixture stirred for 18 hours at 70° C. After cooling to RT, the mixture was diluted with ether, washed with water and brine, dried over MgSO4, and concentrated to give 22.1 g of 3-3 as a white solid.

Provenance & Evidence