反应详情

A mixture of 3-4 (14 g, 30.7 mmol) and hydrazine (5 mL) in ethanol (500 mL) was heated at reflux for 5 hours. The mixture was cooled and concentrated to ⅓ volume, diluted with 300 mL MTBE, and filtered. The filtrate was concentrated to give 7.1 g of 3-5 as a brown oil, contaminated with a small amount of phthalhydrazide.

1. temperaturewas heated
2. temperatureat reflux for 5 hours
3. temperatureThe mixture was cooled
4. concentrationconcentrated
5. additiondiluted with 300 mL MTBE
6. filtrationfiltered
7. concentrationThe filtrate was concentrated