Hydrochloric Acid → HCID 69841186, compound

Participants

Reaction Conditions

Reaction Steps

A 6-liter reactor is charged with 900 ml of ethanol, 302 g of zinc powder and 363 g of 4-mercapto-3-nitro-N-phenyl-benzamide. The mixture is heated to 65° C. and then 992 g of 34% concentrated hydrochloric acid are added within two hours while maintaining the reaction temperature below 70° C. The mixture is stirred at reflux for 2.5 hours and 50 g more of concentrated hydrochloric acid are added. A white suspension is formed. The reaction mixture is cooled to 70° C., filtered hot, and washed with 26 liters of water. The white product is dried at 80° C. under vacuum overnight. 264.6 g (72.6%) of 4-mercapto-3-nitro-N-phenyl-benzamide zinc salt are obtained.

Provenance & Evidence