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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 993331Generated: October 26, 2026

1,2-Dichloroethane → 6-Hydroxy-2-(4-hydroxyphenyl)-3-(4-(2-piperidinoethoxy)-benzoyl]benzo[b]thiophene Hydrochloride 1,2-Dichloroethane

https://huagongshe.com/reaction/993331

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantRaloxifene HydrochlorideHCID 54900—
Product6-Hydroxy-2-(4-hydroxyphenyl)-3-(4-(2-piperidinoethoxy)-benzoyl]benzo[b]thiophene Hydrochloride 1,2-DichloroethaneHCID 9916879—

Reaction Steps

The X-ray structure clearly shows that the crystalline material is a 1,2-dichloroethane solvate having a 1:2 ratio of molecules of 1,2-dichloroethane to molecules of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]-benzo[b]-thiophene hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06472531B1
Source datasetuspto-grants-2002_10
ORD IDord-631c84efdcd94af28a63678c68e7ede4
Source noteuspto-grants-2002_10