HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-CHLORO-4-CHLOROMETHYL-7-HYDROXY-CHROMEN-2-ONE → HCID 18410349, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-CHLORO-4-CHLOROMETHYL-7-HYDROXY-CHROMEN-2-ONE | HCID 5423976 | — |
| Reactant | 6-Bromo-4-(chloromethyl)-7-hydroxy-2H-1-benzopyran-2-one | HCID 18410344 | — |
| Product | HCID 18410349 | HCID 18410349 | 28% |
Reaction Steps
This compound was prepared by the same method as compound 5, starting with compound 12 rather than compound 11, to yield 75.4 mg (0.281 mmol, 28% yield) of compound 4 as an oil. 1H NMR (CDCl3+5% CD3OD) δ 7.43 (1H, s), 6.85 (1H, s), 6.25 (1H, s), 5.16 (2H, s), 3.30 (1H, s), 2.14 (3H, s); MS (ES, negative) 267.2 and 269.1; UV (KMOPS, pH 7.2) λmax (ε) 370 nm (16,000 M−1cm−1). ps 3,6,8-Tribromo-4-chloromethyl-7-hydroxycoumarin (13).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06472541B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-5323cd566c3f4acf885aa8d3686b2616 |
| Source note | uspto-grants-2002_10 |