Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 993388Generated: October 26, 2026

4-(4-Dimethylaminosulfonylbenzyl)-nitrobenzene → 4-(4-Dimethylaminosulfonylbenzyl)-phenylamine

https://huagongshe.com/reaction/993388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Dimethylaminosulfonylbenzyl)-nitrobenzeneHCID 21876958—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
Product4-(4-Dimethylaminosulfonylbenzyl)-phenylamineHCID 21877038102.2%

Reaction Steps

4-(4-Dimethylaminosulfonylbenzyl)-nitrobenzene (311 mg) was dissolved in ethyl acetate and hydrogenated at 40 psi using a 10% palladium on carbon catalyst for 2 hours. The mixture was filtered, and solvents evaporated to give 4-(4-dimethylaminosulfonylbenzyl)-phenylamine as a white solid (288 mg, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06472536B1
Source datasetuspto-grants-2002_10
ORD IDord-806768d56c3e4ade8199e61b943a9879
Source noteuspto-grants-2002_10