1-Methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid → N-(3-fluoro-4-(2-(4-(methylcarbamoyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
Reaction equation
[CH3:29][n:30]1[c:31](=[O:39])[c:32]([C:36](=[O:37])[OH:38])[cH:33][cH:34][cH:35]1.[NH2:1][c:2]1[cH:3][c:4]([F:28])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][cH:12]2)[cH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([C:20](=[O:21])[NH:22][CH3:23])[cH:24][cH:25]2)[s:15]3)[cH:26][cH:27]1>>[NH:1]([c:2]1[cH:3][c:4]([F:28])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][cH:12]2)[cH:13][c:14](-[c:16]2[cH:17][cH:18][c:19]([C:20](=[O:21])[NH:22][CH3:23])[cH:24][cH:25]2)[s:15]3)[cH:26][cH:27]1)[C:36]([c:32]1[c:31](=[O:39])[n:30]([CH3:29])[cH:35][cH:34][cH:33]1)=[O:37]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-53f265ce565643708dbe52e144abc270
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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