Dichloromethane → Pyrazolo[3,4-d]pyrimidine 5

HRID 99606Notes

Reaction equation

HRID 99606 reaction equation
[C:33]([c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1)(=[O:40])[Cl:41].[Cl:42][CH2:43][Cl:44].[NH2:1][c:2]1[c:3]([O:31][CH3:32])[cH:4][c:5](-[c:8]2[n:9][n:10]([CH:18]3[CH2:19][CH2:20][CH:21]([N:24]4[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]4)[CH2:22][CH2:23]3)[c:11]3[n:12][cH:13][n:14][c:15]([NH2:17])[c:16]23)[cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([O:31][CH3:32])[cH:4][c:5](-[c:8]2[n:9][n:10]([CH:18]3[CH2:19][CH2:20][CH:21]([N:24]4[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]4)[CH2:22][CH2:23]3)[c:11]3[n:12][cH:13][n:14][c:15]([NH2:17])[c:16]23)[cH:6][cH:7]1)[C:33]([c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1)=[O:40]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 7412Benzoyl chlorideHCID 208170343-(4-amino-3-methoxyphenyl)-1-[4-(4-methylpiperazino)-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Product 1

HCID 6539956Pyrazolo[3,4-d]pyrimidine 5

Sources & evidence

ORD record
ord-6a7557d79b514f0ca3c38ed1010e18cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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