2-Chloropyridine-3-sulfonyl chloride → 8-(2-Chloro-pyridine-3-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[Cl:23][c:24]1[n:25][cH:26][cH:27][cH:28][c:29]1[S:30](=[O:31])(=[O:32])[Cl:33].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:20])[C:12]3([CH2:13][CH2:14]2)[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:21])[F:22]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:20])[C:12]3([CH2:13][CH2:14]2)[CH2:15][CH2:16][N:17]([S:30]([c:29]2[c:24]([Cl:23])[n:25][cH:26][cH:27][cH:28]2)(=[O:31])=[O:32])[CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:21])[F:22]Participants
3
Sources & evidence
- ORD record
- ord-fc6e1c8a1bc9412699d0e1b93bdb6ac4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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