N-氨基-3-氮杂双环[3.3.0]辛烷盐酸盐 (HCID 16213802)

名称与标识

首选名称: Hexahydrocyclopenta(c)pyrrol-2(1H)-amine monohydrochloride
IUPAC: 3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-amine;hydrochloride
中文名: N-氨基-3-氮杂双环[3.3.0]辛烷盐酸盐
英文名: 3-Amino-3-azabicyclo[3.3.0]octane hydrochloride
分子式: C7H15ClN2
分子量: 162.66

名称与别名

EINECS 261-131-9Hexahydrocyclopenta(c)pyrrol-2(1H)-amine monohydrochlorideCyclopenta[c]pyrrol-2(1H)-amine, hexahydro-, monohydrochlorideHexahydrocyclopenta[c]pyrrol-2(1H)-amine monohydrochlorideCyclopenta(c)pyrrol-2(1H)-amine, hexahydro-, monohydrochlorideRefChem:786163261-131-958108-05-73-Amino-3-azabicyclo[3.3.0]octane hydrochlorideHexahydrocyclopenta[c]pyrrol-2(1H)-amine hydrochlorideMFCD007924513,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-amine;hydrochloride

展开更多名称

氨基杂环格列齐特08氨基双环盐酸盐格列齐特中间体2格列齐特杂质10氨基氮杂双环盐酸盐格列齐特侧链 S10格列齐特杂质3盐酸盐格列齐特杂质1盐酸盐N-氨基-3-氮杂双环N-Amino-3-Azabicyclo[3,3,0]-Octan HclGliclazide Impurity 11Gliclazide Intermediate 2Gliclazide Impurity 1 HCl3-aMino-3-Azabicyclooctane HClN-Amino-azabicyclo-[3,3,0]-octaneN-Amino-3-Azabicyclo[3.3.0]-OctanGliclazide Impurity 9 (Hydrochloride)N-amino-3-azabicycio[3.3.0] octane HCL

3-AMINO-3-AZABICYCLO[3,3,0]OCTANE HYDROCHLORIDECyclopenta[c]pyrrol-2(1H)-amine, hexahydro-, hydrochloride (1:1)N-amino-3-aza bicyclo(3,3,0) octane HCLN-AMINO-3-AZABICYCLO[3.3.0]OCTANE HCLHexahydrocyclopenta[c]pyrrol-2(1H)-amine; N-Amino-3-azabicyclo[3.3.0]octane Hydrochloride; NAZA HydrochlorideGliclazide Impurity 1Gliclazide Impurity 10SCHEMBL1027991

数据库标识

CAS: 58108-05-7
PubChem CID: 16213802
DTXSID: DTXSID40973688
EC Number: 261-131-9

性质

结构计算性质

极性表面积: 29.3 Å²
氢键供体: 2
氢键受体: 2
可旋转键: 0
重原子: 10
形式电荷: 0
复杂度: 101

物理化学性质

熔点: 170 · 170-174 °C(lit.)
储存条件: Inert atmosphere,Room Temperature
溶解度: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly),Water (Slightly)
形态: Solid
颜色: Off-White to Pale Beige
稳定性: Hygroscopic
InChI: InChI=1S/C7H14N2.ClH/c8-9-4-6-2-1-3-7(6)5-9;/h6-7H,1-5,8H2;1H
InChIKey: WPYNXKFLSQEEFE-UHFFFAOYSA-N
SMILES: NN1CC2CCCC2C1.Cl
CAS 数据库: 58108 · 58108-05-7(CAS DataBase Reference)

安全与法规

GHS分类

GHS Classification · 6 条

This chemical does not meet GHS hazard criteria for 2.2% (1 of 46) of reports.

Warning

H315 (97.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (97.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 46 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 46 reports by companies.；There are 6 notifications provided by 45 of 46 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危害信息

Regulatory InformationStatus: Active Update: 02-07-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23490

Hazard Classes and CategoriesSkin Irrit. 2 (97.8%)；Eye Irrit. 2 (97.8%)；STOT SE 3 (97.8%)

法规信息

Regulatory InformationStatus: Active Update: 02-07-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23490

安全数据

wgk: 3
存储类别: 11 - Combustible Solids
安全说明: 26-36
危险品标志: Xi
危险性类别: Eye Irrit. 2Skin Irrit. 2STOT SE 3
危险类别码: 36/37/38

化学与工业

应用领域

用途N-氨基-3-氮杂双环[3.3.0]辛烷盐酸盐用作磺酰脲降血糖药格列齐特的合成反应物。用作抗糖尿病药。

用途用作药物格列齐特中间体;Glicianide intermediate格列奇特中间体;

上下游产品信息

上游原料

甲苯硼氢化钾

下游产品

格列齐特

试剂价格

XW025810805702 · 500g: 3-氨基-3-氮杂双环[3.3.0]辛烷盐酸盐Hexahydrocyclopenta[c]pyrrol-2(1H)-amine hydrochloride — 1350元
XW025810805701 · 100g: 3-氨基-3-氮杂双环[3.3.0]辛烷盐酸盐Hexahydrocyclopenta[c]pyrrol-2(1H)-amine hydrochloride — 271元

供应商50 家

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

济南百隆化学有限公司[email protected] · [email protected]

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

Hebei shuoxi biotechnology co. LTD+8613081092107

关联笔记

加载中…

N-氨基-3-氮杂双环[3.3.0]辛烷盐酸盐

基本信息