化工社化工社化学信息打印报告 · 仅供科研参考
氯化亚锡
绿化锡 · 氯化亞錫 · 二氯亚锡 · 二氯化锡 · 氯化亚锡 · 無水氯化錫 · 无水二氯化锡 · 无水氯化锡粉
标识与物理属性
| CAS No. | 7772-99-8 |
|---|---|
| 分子式 | Cl2Sn |
| 平均分子量 | 189.61 g/mol |
| SMILES | [Cl][Sn][Cl] |
| InChIKey | AXZWODMDQAVCJE-UHFFFAOYSA-L |
| PubChem CID | 24479 |
| ChEMBL | CHEMBL2297930 |
| EC No. | 231-868-0 |
| 中文名 | 氯化亚锡 |
化学与物理性质
| 极性表面积 | 0 |
|---|---|
| 氢键供体 | 0 |
| 氢键受体 | 0 |
| 可旋转键 | 0 |
| 重原子 | 3 |
| 形式电荷 | 0 |
| 复杂度 | 2.8 |
| 物质类别 | Metals -> Metals, Inorganic CompoundsCorrosives |
| 化妆品 | Reducing |
| 气味 | Odorless |
| 食品添加剂 | ANTIOXIDANT -> FDA Substance added to food |
| 密度 | 3.95 at 77 °F (NTP, 1992) - Denser than waterwill sink3.90 g/cu cmWhite monoclinic crystalsdecomposes @ 37 °C, density 2.71 g/cu cm, souluble in water, ethanol, NaOH, very soluble in HCl. /Dihydrate/3.95 g/cm³2.71 @25 °C |
| Color/Form | White, ortho rhombic crystalsOrthorhombic crystalline mass or flakesfatty appearance |
| 溶解性 | less than 1 mg/mL at 72 °F (NTP, 1992)Freely solubleWater: soluble in less than its own weight of water, but it forms an insoluble basic salt with excess waterEthanol: solubleA white crystalline solid, sol in methanol /Dihydrate/Sol in methyl acetate, isobutyl alcoholpractically insol in petroleum naphtha, xyleneSOL IN PYRIDINE, ETHYL ACETATEH2O: solubleSoluble in water, alkalies, alcohol, methyl ethyl ketone, methyl acetate and acetone. |
| 沸点 | 1206 °F at 760 mmHg (NTP, 1992)623 °C623 °C @760 [mm Hg]652 °C(lit.) |
| Decomposition | When heated to decomp it emits toxic fumes of Cl- /chloride/.Decomposed by hot water.652 °C |
| 熔点 | 475 °F (NTP, 1992)246 °C246.8 °C246 °C(lit.) |
| 蒸气压 | 0 mmHg at 68 °F (NTP, 1992)3.3 kPa @ 427.9 °C0Pa at 20℃ |
| Food Contact Substances | FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR |
| 闪点 | 652°C |
| 储存条件 | Store below +30°C. |
| 形态 | powder |
| 颜色 | White |
| 比重 | 3.95 |
| pH | 2.0 (100g/l, H2O, 20℃) |
| 敏感性 | Air Sensitive & Hygroscopic |
| 晶体结构 | PbCl2 type |
| 晶系 | Nogata |
| Merck | 14,8783 |
| 空间群 | Pnma |
| 晶格常数 | a/nmb/nmc/nmα/oβ/oγ/oV/nm30.7790.4430.9219090900.318 |
| 暴露限值 | ACGIH: TWA 2 mg/m3NIOSH: IDLH 100 mg/m3 |
| 稳定性 | Stable, but moisture sensitive. Incompatible with strong bases, strong oxidizing agents, reactive metals, hydrogen peroxide, water. |
| 化妆品成分功效 | REDUCING |
| InChI | 1S/2ClH.Sn/h2*1H/q+2/p-2 |
| InChIKey | AXZWODMDQAVCJE-UHFFFAOYSA-L |
| SMILES | Cl[SnH2]Cl |
| LogP（油水分配系数） | -2.15 at 20℃ |
| CAS 数据库 | 7772-99-8(CAS DataBase Reference) |
| EPA化学物质信息 | Tin dichloride (7772-99-8) |
安全与法规
| GHS 分类 | This chemical does not meet GHS hazard criteria for 0.5% (4 of 774) of reports.DangerH290 (36.2%): May be corrosive to metals [Warning Corrosive to Metals]P234, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P333+P317, P337+P317, P362+P364, P363, P390, P391, P403+P233, P405, P406, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 774 reports by companies from 50 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 法规信息 | Chemical: Tin chloride (SnCl2)Regulation (EC) No 1331/2008Tin chloride (SnCl2) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Tin chloride (SnCl2) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 01-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13167Tin (II) chloride, anhydrous: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 其他安全信息 | IMAP assessments - Tin chloride (SnCl2): Human health tier I assessment |
| 运输标签（DOT） | Corrosive |
| 火灾危害 | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| 火灾可能性 | Ignition on contact with bromine trifluoride. |
| 健康危害 | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: |
| 危害概述 | A skin irritant[Hawley] A strong reducing agentAn eye and respiratory tract irritant[ICSC] A strong reducing agentA skin and eye irritant[CAMEO] A skin and eye irritantMay cause skin sensitization[eChemPortal: ERMA] Harmful if swallowedCauses burnsPossible reproductive toxinA corrosive substance that can cause injury to the skin, eyes, and respiratory tract[MSDSonline] See Tin and inorganic compounds. |
| FDA 要求 | Stannous chloride is a food additive permitted for direct addition to food for human consumption, as long as 1) the quantity of the substance added to food does not exceed the amount reasonably required to accomplish its intended physical, nutritive, or other technical effect in food, and 2) any substance intended for use in or on food is of appropriate food grade and is prepared and handled as a food ingredient.Substance added directly to human food affirmed as generally recognized as safe (GRAS).Stannous chloride used as a chemical preservative in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice. |
| 反应性基团 | Salts, Acidic |
| 联合国分类 | UN Hazard Class: 8UN Pack Group: III |
| Special Reports | DHHS/NTPToxicology & Carcinogenesis Studies of Stannous Chloride in F344/N Rats and B6C3F1 Mice (Feed Study) Technical Report Series No. 231 (1982) NIH Publication No. 82-1787DHHS/ATSDRToxicological Profile for Tin TP-91/27 (1992) |
| Reactivity Alerts | Strong Reducing Agent |
| 消防 | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water. |
| 急救措施 | Fresh air, rest.Remove contaminated clothes. Rinse skin with plenty of water or shower.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Give one or two glasses of water to drink. Refer for medical attention . |
| 急救 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 安全储存 | Separated from incompatible materials and food and feedstuffs. Dry. |
| 储存条件 | KEEP TIGHTLY CLOSED, IN A COOL PLACE. /DIHYDRATE/CONTAINERS: BOTTLESDRUMS. |
| 清理方法 | If ... stannous chloride ... is spilled or leaked, the following steps should be taken: 1. Ventilate area of spill or leak. 2. Collect spilled or leaked material in the most convenient and safe manner for reclamation or for disposal. ... Liquid containing inorganic tin compounds should be absorbed in vermiculite, dry sand, earth, or a similar material. |
| 非火灾泄漏应对 | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: |
| 处置方法 | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
| 泄漏处置 | Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations. |
| Preventive Measures | If employees' clothing may have become contaminated with solid stannous chloride ... employees should change into uncontaminated clothing before leaving the work premises. ... Non-impervious clothing which becomes wet with stannous chloride should be removed promptly and not reworn until the stannous chloride is removed from the clothing.Clothing contaminated with stannous chloride /or/ stannic chloride ... should be placed in closed containers for storage until it can be discarded or until provision is made for the removal of contaiminant from the clothing. If the clothing is to be laundered or otherwise cleaned to remove the contaminant, the person performing the operation should be informed of contaminant's hazardous properties.Skin that becomes contaminated with stannous chloride should be promptly washed to remove any stannous chloride. Employees who handle stannous chloride, stannic chloride ... should wash their hands thoroughly before eating, smoking, or using toilet facilities.SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. All contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place. |
| Isolation and Evacuation | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: |
| Eye Prevention | Wear safety goggles or eye protection in combination with breathing protection. |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| 健康影响 | Ingestion of large amounts of inorganic tin compounds can cause stomachache, anemia, and liver and kidney problems. (L307, L308) |
| 不良影响 | Dermatotoxin - Skin burns. |
| 暴露途径 | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.Oral (L308)inhalation (L308)dermal (L308) |
| 毒性概述 | Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) |
| Signs and Symptoms | Cough. Sore throat.Redness. Pain.Abdominal pain. Diarrhoea. Nausea. Vomiting.Inorganic or organic tin compounds placed on the skin or in the eyes can produce skin and eye irritation. (L308) |
| Ongoing Test Status | The following link will take the user to the National Toxicology Program (NTP) Test Agent Search Results page, which tabulates all of the "Standard Toxicology & Carcinogenesis Studies", "Developmental Studies", and "Genetic Toxicity Studies" performed with this chemical. Clicking on the "Testing Status" link will take the user to the status (i.e., in review, in progress, in preparation, on test, completed, etc.) and results of all the studies that the NTP has done on this chemical. [http://ntp-apps.niehs.nih.gov/ntp_tox/index.cfm?fuseaction=ntpsearch.searchresults&searchterm=7772-99-8] |
| ICSC Environmental Data | The substance is harmful to aquatic organisms. |
| Human Toxicity Excerpts | In this study tin(II), as stannous chloride, is readily taken up by human white blood cells and can cause damage to DNA. Damage was detected in white blood cells after exposure to 10-50 uM tin(II) for 30 minutes at either 0 deg or 37 °C.Organotin compounds examined in this study exhibited a relative order of potency for induction of in vitro hemolysis in human erythrocytes as follows: tri-n-butylitin > tri-n-propyltitn > tetra-n-butyltin > triphenyltin chloride > tri-n-ethyltin bromide > dibutyltin dichloride > stannous chloride > tri-n-methyltin chloride + butyltin chloride dihydroxide. |
| Carcinogen Classification | Stannous chlorideTR-231: Carcinogenesis Bioassay of Stannous Chloride (CASRN 7772-99-8) in F344/N Rats and B6C3F1/N Mice (Feed Study) (1982 )06/23/81Equivocal EvidenceNo Evidence |
| Non-Human Toxicity Excerpts | THERE IS 1 REPORT ... OF PARALYSIS IN DOG AFTER LARGE DOSE (500 MG/KG) OF STANNOUS CHLORIDE IN MILK.SEVERE GROWTH RETARDATION & OTHER SIGNS OF TOXICITY OCCURRED WITH STANNOUS CHLORIDE ... @ FEEDING LEVELS OF 0.3% /TO RATS/.DOSE EFFECT OF INORGANIC TIN WAS EXAMINED IN MALE WISTAR RATS ORALLY ADMIN STANNOUS CHLORIDE (1, 3, 10, & 30 MG TIN/KG). EACH DOSE WAS ADMIN 6 TIMES @ 12 HR INTERVALS. DECREASES IN GASTRIC SECRETION, DUODENAL ALKALINE PHOSPHATASE & HEPATIC PHOSPHORYLASE ACTIVITIES, SERUM CALCIUM CONCN, FEMORAL CALCIUM CONTENT WERE FOUND. AT 3 MG/KG, THE CALCIUM CONTENT IN EPIPHYSIS OF THE FEMUR WAS SIGNIFICANTLY DECREASED BUT NOT AT 1 MG/KG. RESULTS SUGGEST THAT THE CRITICAL ORGAN IN INORGANIC TIN TOXICITY IS BONE.WHEN ADMIN ORALLY TO RATS TWICE DAILY FOR 3 DAYS, STANNOUS CHLORIDE (3 MG TIN/100 G) INCR SERUM GLUCOSE CONCN & DECR SERUM INSULIN LEVEL AFTER A SINGLE ORAL GLUCOSE LOAD (0.2 G/100 %).For more Non-Human Toxicity Excerpts (Complete) data for STANNOUS CHLORIDE (21 total), please visit the HSDB record page. |
| Populations at Special Risk | Skin disease: Certain inorganic tin cmpd other than oxides are primary skin irritants. Persons with existing skin disorders may be more susceptible to the effects of these agents. |
| 州饮用水指南 | (MN) MINNESOTA 4000 ug/l /Tin/ |
| 水危害等级（WGK） | 1 |
| TSCA 清单状态 | TSCA listed |
| 毒性 | LD50 in mice, rats (mg/kg): 1710.0, 2000.0 orally271.0, 316.0 i.p.34.8, 43.0 i.v. (Singh, Junnarkar) |
| RTECS 号 | XP8700000 |
| 包装类别 | II |
| 危险类别 | 8Acute Tox. 4 InhalationAcute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Met. Corr. 1Skin Corr. 1BSkin Sens. 1STOT RE 2 OralSTOT SE 3 |
| 储存类别 | 8B - Non-combustible corrosive hazardous materials |
| 安全说明（S） | 26-36/37/39-45-61-60-53 |
| 海关编码 | 28273990 |
| 危险品标志 | C,Xi,N |
| 危险类别码（R） | 22-34-36/37/38-37-68-50/53-48/22-43-20-63 |
| 毒害物质数据 | 7772-99-8(Hazardous Substances Data) |
| 运输编号（UN） | UN 3260 8/PG 3 |
用途与应用
用途
氯化亚锡用作还原剂、媒染剂、分析试剂及脱水剂，也用作有机合成催化剂。
应用
无水二氯化锡用于染料、香料、制镜、电镀等工业；并用作超高压润滑油、漂白剂，用作还原剂、媒染剂、脱色剂和分析试剂，用于银、砷、钼、汞的测定。强还原剂。测定血清中无机磷及碱性磷酸酯酶活力。钼蓝法测定土壤及植株的含磷量。有机反应催化剂。用作还原剂、媒染剂、酸性镀锡，做主盐使用。用于玻璃制镜工业，作镀硝酸银的敏化剂，使镀膜亮度好，在ABS电镀时加入本品镀层不易脱落。
用途
用于银、砷、钼等的测定，也用作媒染剂、还原剂