2-甲基哌嗪 (HCID 66057)

概述

structure in first source

名称与标识

首选名称: 2-Methylpiperazine
IUPAC: 2-methylpiperazine
中文名: 2-甲基哌嗪
英文名: 2-Methylpiperazine
分子式: C5H12N2
分子量: 100.16

名称与别名

2-Methylpiperazine109-07-9Piperazine, 2-methyl-2-methyl piperazineD0LWN1061PNSC-5277DTXSID10219002(s)-methyl piperazineRefChem:88369DTXCID901900203-644-2MFCD00005954

展开更多名称

2-甲基哌嗪(±)-2-甲基哌嗪2-甲基哌嗪,98%(+/-)-2-甲基哌嗪2-甲基哌嗪, 97+%(±)-2-甲基哌嗪,98%MP2MPRZ2-methyl-piperazinPiperazine,2-methyl-2-Methylpiperazine>2-Methylpiperazine,98%2-Methylpiperazine ,99%2-Methylpiperazine, 97+%

2-METHYL-PIPERAZINE(+/-)-2-MethylpiperazineEINECS 203-644-2BRN 0383566UNII-D0LWN1061P2methylpiperazine2-methylpiperazin2-methypiperazine

数据库标识

CAS: 109-07-9
PubChem CID: 66057
DTXSID: DTXSID1021900
UNII: D0LWN1061P
EC Number: 203-644-2
Nikkaji: J68.144J

性质

结构计算性质

XLogP: -0.4
极性表面积: 24.1 Å²
氢键供体: 2
氢键受体: 2
可旋转键: 0
重原子: 7
形式电荷: 0
复杂度: 54

物理化学性质

熔点: 61 · 61-63 °C (lit.)
沸点: 155 °C/763 · 155 °C/763 mmHg (lit.)
密度: 0.817 g/cm · 0.817 g/cm
折射率: 1.4378 · 1.4378 (estimate)
闪点: 149 °F · 149 °F
储存条件: Keep in dark place,Inert atmosphere,Room temperature
溶解度: 435 g/l · 435g/l
酸度系数(pKa): 1 · pK1:5.62(+2);pK2:9.60(+1) (25°C)
形态: Crystalline Powder, Crystals and/or Chunks
颜色: White to yellow
PH值: 11 · 11-12 (50g/l, H2O)
水溶解性: 78 g/100 · 78 g/100 mL (25 ºC)
敏感性: Air Sensitive & Hygroscopic
BRN: 383566 · 383566
Henry's Law Constant: 5 · 5.0×103 mol/(m3Pa) at 25℃, Nguyen (2013)
InChI: 1S/C5H12N2/c1-5-4-6-2-3-7-5/h5-7H,2-4H2,1H3
InChIKey: JOMNTHCQHJPVAZ-UHFFFAOYSA-N
SMILES: CC1CNCCN1
CAS 数据库: 109 · 109-07-9(CAS DataBase Reference)
NIST化学物质信息: 2 · Piperazine, 2-methyl-(109-07-9)
EPA化学物质信息: 2 · Piperazine, 2-methyl- (109-07-9)

化学性质

无色晶体，有吸湿性，具有典型胺的气味，易溶于水和丙酮。

安全与法规

GHS分类

GHS Classification · 4 条

Danger

H228 (99.4%): Flammable solid [Danger Flammable solids]

P210, P240, P241, P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 154 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危害信息

Regulatory InformationStatus: Active Update: 10-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19024

Hazard Classes and CategoriesFlam. Sol. 1 (99.4%)

安全数据

F: 10
wgk: 2
tsca: TSCA listed
RTECS号: TM1225020
包装类别: III
危险等级: 4.1
存储类别: 4.1B - Flammable solid hazardous materials
安全说明: 16-26-36/37/39-36
海关编码: 29339900
危险品标志: F,Xi
危险性类别: Eye Dam. 1Flam. Sol. 1Skin Corr. 1B
危险类别码: 11-36/37/38
危险品运输编号: UN 1325 4.1/PG 2

化学与工业

用途与制造

General Manufacturing InformationPiperazine, 2-methyl-: ACTIVE

应用领域

用途医药中间体，是合成洛美沙星的原料

上下游产品信息

上游原料

乙二胺环氧丙烷 3-Methyl-1-benzyl-piperazine 2,5-二甲基哌嗪 2,6-二甲基哌嗪 D-无水葡萄糖

下游产品

2-甲基吡嗪洛美沙星替马沙星 (±)-1-环丙基-6-氟-1,4-二氢-5-甲基-7-(3-甲基-1-哌嗪基)-4-氧-3-喹啉羧酸盐酸洛美沙星 4-叔丁氧羰基-2-甲基哌嗪 (R)-(-)-2-甲基哌嗪 DL-氨基丙醇 1,2-二甲基哌嗪哌嗪

试剂价格

M1179 · 25G: 2-甲基哌嗪2-Methylpiperazine — 230元
M1179 · 500G: 2-甲基哌嗪2-Methylpiperazine — 1990元

供应商50 家

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

科瑞迪化学400-821-5857 021-64326257 · [email protected]

关联笔记

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2-甲基哌嗪

基本信息

概述