十六胺

Hexadecylamine

HCID 8926CAS 143-27-1

基本信息

标准SMILES
CCCCCCCCCCCCCCCCN
InChIKey
FJLUATLTXUNBOT-UHFFFAOYSA-N
分子式
C16H35N
平均分子量
241.46 g/mol
单同位素质量
241.27695012

概述

Hexadecylamine is a white solid. (NTP, 1992)

名称与标识

首选名称
Hexadecylamine
IUPAC
hexadecan-1-amine
中文名
十六胺
英文名
1-Hexadecylamine
分子式
C16H35N
分子量
241.46

名称与别名

Hexadecylamine1-HexadecylamineCetylamine143-27-1hexadecan-1-amine1-Hexadecanamine1-AminohexadecaneN-HEXADECYLAMINEPalmitaminen-CetylamineHexyldecylaminePalmitylamine
展开更多名称
十六棕榈胺十六胺鲸蜡胺鯨蠟胺十六铵正十六胺十六烷基胺正十六烷胺1-十六胺HDAHADArmeen 16
Armeen 16DMonohexadecylamineAlamine 6Palmityl amineNissan amine PBCetylaminAlamine 6D1-Hexadecanylamine

数据库标识

CAS
143-27-1、68037-95-6
PubChem CID
8926
DTXSID
DTXSID7025390
ChEMBL
CHEMBL1534653
ChEBI
CHEBI:165594
UNII
O2H0Q02M4P
EC Number
205-596-8
Nikkaji
J6.125E

性质

结构计算性质

XLogP
7.4
极性表面积
26 Ų
氢键供体
1
氢键受体
1
可旋转键
14
重原子
17

实验与物化性质

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
CosmeticsAntistatic
SpringerMaterials PropertiesBoiling point
Density · 2 条

0.8129 at 68 °F (NTP, 1992) - Less dense than water; will float

0.8129 @ 20°C

Solubilityless than 1 mg/mL at 72 °F (NTP, 1992)
Flash Point285 °F (NTP, 1992)

物理化学性质

熔点
43 · 43-45 °C (lit.)
沸点
330 °C · 330 °C (lit.)
密度
0 · 0,813 g/cm3
蒸气压
1 mm · <1 mm Hg ( 20 °C)
折射率
1.4496 · 1.4496
闪点
285 °F · 285 °F

化学性质

白色片状结晶。熔点46.77℃,沸点332.5℃,187(2.0kPa)177.9℃(1.33kPa),162-165℃(0.69kPa),相对密度0.8129(20/4℃),折光率1.4496,闪点140℃。溶于乙醇、乙醚、丙酮、苯和氯仿,不溶于水。可吸收二氯化碳。

安全与法规

GHS分类

GHS Classification · 6 条

Danger

H314 (98%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P273, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 50 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

危害信息

Regulatory Information · 3 条

Chemical: 1-Hexadecanamine

Status: Active Update: 30-09-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/29504

Hexadecylamine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Primary aliphatic (C12-22) and fatty amines: Human health tier II assessment
DOT LabelCorrosive
Fire HazardsThis chemical is combustible. (NTP, 1992)
Health HazardsExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Hazards SummaryMay cause skin, eye, and mucous membrane irritation; [CAMEO] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS] See Decylamine.

安全与防护

Fire FightingFires involving this chemical can be controlled with a CO2, dry chemical, or Halon extinguisher. (NTP, 1992)
First Aid · 1 条

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 条

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Protective Action Criteria (PAC) · 3 条

0.66 [mg/m3]

7.2 [mg/m3]

43 [mg/m3]

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

毒理信息

Adverse EffectsDermatotoxin - Skin burns.

安全数据

F
34
wgk
2
tsca
TSCA listed
毒性
mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),National Technical Information Service. Vol. AD691-490,
RTECS号
ML9100000
包装类别
III

化学与工业

用途与制造

UsesUsed to make other chemicals; [CAMEO]
Use ClassificationCosmetics -> Antistatic
General Manufacturing Information1-Hexadecanamine: ACTIVE
应用领域 · 3 条

用途用于制取树脂、杀虫剂和高级洗涤剂。

用途用于纤维助剂、化肥抗结块剂、浮选剂等

用途用于制树脂、杀虫剂和高级洗涤剂等。由软脂酸通氨脱水成十六腈,再加压加氢使腈转化而成。

制备方法

生产方法由棕榈脯经还原而得。将3份棕榈脯溶于30份无水乙醇中,慢慢加入金属钠4份进行还原。反应放热,使反应物呈液体状态。当加入的金属钠只能部分溶解时,可加热至60℃,并逐渐升温至120℃,始终使金属钠不全部消失。反应完全后趁热倾入水中,加入稍过量的盐酸,将生成的十六胺盐酸盐结晶滤出,用少量稀盐酸洗涤后压干。将此盐酸用20%氯氧化钠碱化,减压蒸馏,得十六胺。

试剂价格

H0074 · 5G
十六胺Hexadecylamine — 80元
H0074 · 25G
十六胺Hexadecylamine — 150元

供应商50 家

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]

相关反应

46 条

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