DL-乳酸 → Isonicotinic Acid Amide Lactic Acid

HRID 10119

反应方程式

HRID 10119 反应方程式
C1SC(NC(N)=N)=NC=1CSCCC(NS(N)(=O)=O)=N.[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]>O>[C:21]([NH2:29])(=[O:28])[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1.[C:30]([OH:35])(=[O:34])[CH:31]([CH3:33])[OH:32]

参与物

5

反应物 3

HCID 612DL-乳酸HCID 150744-吡啶甲酰胺HCID 178418935HCID 178418935，化合物2 次

产物 1

HCID 86591738Isonicotinic Acid Amide Lactic Acid

试剂、催化剂与溶剂 1

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂2 次

实验过程

To 1 g of famotidine and 5 g of isonicotinic acid amide were added about 80 ml of water for injection and 2.20 ml of a 100 mg/ml aqueous lactic acid solution, followed by stirring to dissolve them. After complete dissolution of famotidine, water for injection was added to make the total volume 100 ml, whereby an injection solution having a pH of 6.2 and a kinematic viscosity at room temperature of 0.95 centistokes was obtained.

后处理

  1. dissolutionto dissolve them
  2. additionwas added
  3. customa kinematic viscosity at room temperature of 0.95 centistokes was obtained

来源与证据

ORD记录
ord-6961669486c8494bb2c3a3bdd60048e7
来源数据集
uspto-grants-2006_08
专利号
US07094414B2

关联笔记

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