醋酸 → 4-甲砜基苯乙酮

HRID 1065

反应方程式

HRID 1065 反应方程式
[O-][Mn](=O)(=O)=O.[K+].[CH3:7][C:8]([C:10]1[CH:15]=[CH:14][C:13](SC)=[CH:12][CH:11]=1)=[O:9].[S:18]([O-:21])([O-])=[O:19].[Na+].[Na+].[C:24](O)(=O)C>O>[CH3:7][C:8]([C:10]1[CH:15]=[CH:14][C:13]([S:18]([CH3:24])(=[O:21])=[O:19])=[CH:12][CH:11]=1)=[O:9]

参与物

6

反应物 4

HCID 176醋酸HCID 24437无水亚硫酸钠HCID 745014-甲硫基苯乙酮HCID 516875高锰酸钾

产物 1

HCID 825294-甲砜基苯乙酮

试剂、催化剂与溶剂 1

HCID 962聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯]溶剂2 次

实验过程

A solution of 152 g (0.96 mol) of KMnO4 in 3.5 1 of water is introduced into a mixture of 117.1 g (0.7 mol) of 4-(methylthio)acetophenone, prepared in Example 2c, and 292 ml of acetic acid. 2.3 l of water are added and the reaction temperature is allowed to return to room temperature. Saturated sodium sulfite solution is added dropwise until the solution is decolorized. This is left to stand overnight at room temperature. The solid obtained is filtered off, washed copiously with water and recrystallized from 95% ethanol to give 91.5 g of 4-(methylsulfonyl)acetophenone.

后处理

  1. customto return to room temperature
  2. waitThis is left
  3. customThe solid obtained
  4. filtrationis filtered off
  5. washwashed copiously with water
  6. customrecrystallized from 95% ethanol

来源与证据

ORD记录
ord-6d44d87ee23a4984ad13cff1877a23a4
来源数据集
uspto-grants-1998_03
专利号
US05723485

关联笔记

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