(R)-苯氧甲基环氧乙烷 → (R)-3'-[[2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl]amino]-[1,1'-biphenyl]-3-carboxylic acid methyl ester
反应方程式
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][CH2:18][CH2:19][NH2:20])[CH:12]=2)[CH:8]=[CH:9][CH:10]=1)=[O:4].[C:21]1([O:27][CH2:28][C@@H:29]2[O:31][CH2:30]2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][CH2:18][CH2:19][NH:20][CH2:30][C@@H:29]([OH:31])[CH2:28][O:27][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH:12]=2)[CH:8]=[CH:9][CH:10]=1)=[O:4]参与物
3
实验过程
Electrospray MS (positive ion): (M+H) 421.1; from methyl-3′-[(2-aminoethyl)amino]-[1,1′-biphenyl]-3-carboxylate (117 mg) and (R)-(-)-3-(phenyloxy)-1,2-epoxypropane (54 mg).
来源与证据
- ORD记录
- ord-b318394577c74edeb0b3136747dd1ee6
- 来源数据集
- uspto-grants-2001_06