醋酸钠 → HCID 2885488，化合物

HRID 1069129笔记

反应方程式

HRID 1069129 反应方程式
[C:1]1([CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.C([O-])(=O)C.[Na+].[S:26]1[CH2:32][C:30](=[O:31])[NH:29][C:27]1=[S:28]>C(O)(=O)C>[C:1]1([CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=[C:32]3[S:26][C:27](=[S:28])[NH:29][C:30]3=[O:31])=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

参与物

5

反应物 3

HCID 517045醋酸钠HCID 881941HCID 881941，化合物HCID 1201546罗丹宁

产物 1

HCID 2885488HCID 2885488，化合物

试剂、催化剂与溶剂 1

HCID 176醋酸溶剂

实验过程

Under a nitrogen atmosphere in a round bottom flask 4-[(naphth-1-yl)methoxy]benzaldehyde (5.25 g, 20 mmol) was dissolved in 100 ml of acetic acid. To this solution was added sodium acetate (5.74 g, 70 mmol) and rhodanine (2.66 g, 20 mmol). The reaction mixture was raised to the reflux temperature and maintained at this temperature. The progress of the reaction was monitored by thin layer chomratography.

后处理

  1. temperatureThe reaction mixture was raised to the reflux temperature
  2. temperaturemaintained at this temperature

来源与证据

ORD记录
ord-b5bb25d61a364fe3bb4fa90dcbf4ea58
来源数据集
uspto-grants-2001_06
专利号
US06251928B1

反应笔记

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