罗丹宁 → HCID 73753156，化合物

反应方程式

[C:1]([C:9]1[CH:24]=[CH:23][C:12]([CH2:13][O:14][C:15]2[CH:22]=[CH:21][C:18]([CH:19]=O)=[CH:17][CH:16]=2)=[CH:11][CH:10]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:25]1[CH2:31][C:29](=[O:30])[NH:28][C:26]1=[S:27]>>[C:2]1([C:1]([C:9]2[CH:24]=[CH:23][C:12]([CH2:13][O:14][C:15]3[CH:22]=[CH:21][C:18]([CH:19]=[C:31]4[S:25][C:26](=[S:27])[NH:28][C:29]4=[O:30])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)=[O:8])[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参与物

反应物 2

HCID 1201546罗丹宁

HCID 153182414-(4-Benzoylbenzyloxy)benzaldehyde

产物 1

HCID 73753156HCID 73753156，化合物

实验过程

The 4-(4-benzoylbenzyloxy)benzaldehyde was coupled with rhodanine to yield the title compound by admixing the 4-(4-benzoylbenzyloxy)benzaldehyde (2.09 g, 6.3 mmol) with rhodanine (1.0 g, 7.5 mmol), sodium acetate (1.8 g, 22 mmol) and acetic acid (75 ml) in a 250 ml flask. The reaction mixture was heated to reflux and refluxed overnight.

来源与证据

ORD记录: ord-c0a63b33fb6f41d0a69d93977d6b0265
来源数据集: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US06251928B1

反应笔记

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