4-Cyano-4-(2-thienyl)-5-methylhexyl iodide → 1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-fluoro-2-pyridyloxy)ethyl]piperazine
反应方程式
[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6]I)#[N:2].[F:16][C:17]1[N:22]=[C:21]([O:23][CH2:24][CH2:25][N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)[CH:20]=[CH:19][CH:18]=1>>[C:1]([C:3]([C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)([CH:8]([CH3:10])[CH3:9])[CH2:4][CH2:5][CH2:6][N:29]1[CH2:30][CH2:31][N:26]([CH2:25][CH2:24][O:23][C:21]2[CH:20]=[CH:19][CH:18]=[C:17]([F:16])[N:22]=2)[CH2:27][CH2:28]1)#[N:2]参与物
3
实验过程
The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-[2-(6-fluoro-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.
来源与证据
- ORD记录
- ord-7c09fc25d90b488691792c5cae8967d7
- 来源数据集
- uspto-grants-2005_06