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HRID 1255152生成日期：2026年10月26日

2,6-Difluoro-N-(4-(pyridin-2-yl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamide → N-(4-(4-(Dimethylamino)phenyl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-2,6-difluorobenzamide

https://huagongshe.com/reaction/1255152

反应方程式

参与物

角色名称HCID投料
反应物2,6-Difluoro-N-(4-(pyridin-2-yl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamideHCID 24765973—
反应物HCID 178482849HCID 178482849—
产物N-(4-(4-(Dimethylamino)phenyl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-2,6-difluorobenzamideHCID 59004542—

反应步骤

Compound 110 was prepared from 22a and N,N-dimethyl-4-aminophenylmagnesium bromide as described for the preparation of Compound 107.

来源与证据

DOI10.6084/m9.figshare.5104873.v1
专利号US08455658B2
来源数据集uspto-grants-2013_06
ORD IDord-cd41e667059f42368d8d9b1de1b223cb
来源说明uspto-grants-2013_06