环丙乙酸 → N-(Cyclopropylacetyl)-L-alanine Methyl Ester

HRID 133198

反应方程式

HRID 133198 反应方程式
[CH:1]1([CH2:4][C:5]([OH:7])=O)[CH2:3][CH2:2]1.Cl.[CH3:9][O:10][C:11](=[O:15])[C@H:12]([CH3:14])[NH2:13]>>[CH3:9][O:10][C:11](=[O:15])[C@H:12]([CH3:14])[NH:13][C:5](=[O:7])[CH2:4][CH:1]1[CH2:2][CH2:3]1

参与物

3

反应物 2

HCID 138440环丙乙酸HCID 2733257丙氨酸甲酯盐酸盐

产物 1

HCID 53934383N-(Cyclopropylacetyl)-L-alanine Methyl Ester

实验过程

Following General Procedure A above using cyclopropylacetic acid (Aldrich) and L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification was by flash column chromatography using 25% ethyl acetate/hexanes as the eluant.

后处理

  1. customThe reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification

来源与证据

ORD记录
ord-0f0e1de8b7ee492c95e8d53e5344dce5
来源数据集
uspto-grants-2008_06
专利号
US07390801B2

关联笔记

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