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环丙乙酸 → N-(Cyclopropylacetyl)-L-alanine Methyl Ester
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | 环丙乙酸 | HCID 138440 | — |
| 反应物 | 丙氨酸甲酯盐酸盐 | HCID 2733257 | — |
| 产物 | N-(Cyclopropylacetyl)-L-alanine Methyl Ester | HCID 53934383 | — |
反应步骤
Following General Procedure A above using cyclopropylacetic acid (Aldrich) and L-alanine methyl ester hydrochloride (Sigma), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.15 in 25% ethyl acetate/hexanes) and purification was by flash column chromatography using 25% ethyl acetate/hexanes as the eluant.
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US07390801B2 |
| 来源数据集 | uspto-grants-2008_06 |
| ORD ID | ord-0f0e1de8b7ee492c95e8d53e5344dce5 |
| 来源说明 | uspto-grants-2008_06 |