顺-八氢-2H-苯并咪唑-2-酮 → 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)octahydro-2H-benzimidazol-2-one

反应方程式

[I:1][c:2]1[cH:3][c:4]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([c:16]3[c:17]4[cH:18][cH:19][c:20]([CH3:26])[n:21][c:22]4[cH:23][cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:5][cH:6][cH:7]1.[NH:27]1[C:28](=[O:36])[NH:29][CH:30]2[CH:31]1[CH2:32][CH2:33][CH2:34][CH2:35]2>>[c:2]1([N:27]2[C:28](=[O:36])[NH:29][CH:30]3[CH:31]2[CH2:32][CH2:33][CH2:34][CH2:35]3)[cH:3][c:4]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([c:16]3[c:17]4[cH:18][cH:19][c:20]([CH3:26])[n:21][c:22]4[cH:23][cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:5][cH:6][cH:7]1

参与物

反应物 2

HCID 101982顺-八氢-2H-苯并咪唑-2-酮

HCID 574443555-{4-[2-(3-Iodophenyl)ethyl]-1-piperazinyl)2-methylquinoline

产物 1

HCID 574783841-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)octahydro-2H-benzimidazol-2-one

来源与证据

ORD记录: ord-38ca3802d86b43299f0d68b5f7804f9f
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反应笔记

加载中…